A Case of Hypersensitivity to Mosquito Bites without Peripheral Natural Killer Cell Lymphocytosis in a 6-Year-Old Korean Boy.
10.3346/jkms.2013.28.1.164
- Author:
Han Su SEON
1
;
Ji Hyeon ROH
;
Seung Ho LEE
;
Eun Kyeong KANG
Author Information
1. Department of Pediatrics, Dongguk University Ilsan Hospital, Goyang, Korea. silbear@dumc.or.kr
- Publication Type:Case Reports
- Keywords:
Hypersensitivity;
Mosquito Bites;
Epstein-Barr Virus;
Natural Killer Cell
- MeSH:
Child;
Epstein-Barr Virus Infections/complications;
Humans;
Hypersensitivity/*diagnosis/etiology;
Insect Bites and Stings/*diagnosis/pathology;
Killer Cells, Natural/immunology;
Lymphocytosis/complications/pathology;
Male;
Republic of Korea;
Skin/pathology
- From:Journal of Korean Medical Science
2013;28(1):164-166
- CountryRepublic of Korea
- Language:English
-
Abstract:
Hypersensitivity to mosquito bites (HMB) is a rare disease characterized by intense skin reactions such as bulla and necrotic ulcerations at bite sites, accompanied by general symptoms such as high-grade fever and malaise occurred after mosquito bites. It has been suggested that HMB is associated with chronic Epstein-Barr virus (EBV) infection and natural killer (NK) cell leukemia/lymphoma. We describe here a Korean child who presented with 3-yr history of HMB without natural killer cell lymphocytosis. He has been ill for 6 yr with HMB. Close observation and examination for the development of lymphoproliferative status or hematologic malignant disorders is needed.
