The predictive value of red blood cell count, fibrinogen combined with platelet count for risk stratification of acute pulmonary embolism
10.3760/cma.j.issn.1671-0282.2020.06.018
- VernacularTitle:红细胞计数和纤维蛋白原联合血小板计数预测急性肺栓塞危险分层的价值
- Author:
Yan LIU
1
;
Fei TENG
;
Xinhua HE
;
Shubin GUO
Author Information
1. 首都医科大学附属北京朝阳医院急诊科，北京 100020
- From:
Chinese Journal of Emergency Medicine
2020;29(6):829-834
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the predictive value of red blood cell count (RBC), fibrinogen (FBG) combined with platelet count (PLT)for risk stratification of acute pulmonary embolism (PE).Methods:Patients admitted to Beijing Chaoyang Hospital from January 2013 to October 2019 and diagnosed with acute PE were retrospectively collected. According to the risk stratification criteria for PE, the patients were divided into the high/medium risk group and low risk group. The demographic characteristics, previous medical history, parameters of RBC and PLT, and FBG of the two groups were compared.Results:Totally 696 patients were selected in the study, of them, 193 patients were in the high/medium risk group and 503 in the low risk group. RBC and hematocrit (HCT) in the high/medium risk group were significantly higher than those in the low risk group, but FBG and PLT in the high/medium risk group were significantly lower than those in the low risk group (all P<0.05). There was no significant difference in age, gender, previous medical history, hemoglobin (HGB), HCT, mean corpuscular volume (MCV), mean corpuscular hemogloin (MCHC), red blood cell distribution width (RDW), platelet distribution width (PDW), mean platelet volume (MPV), and platelet large cell rate (P-LCR) between the two groups. Logistic regression analysis showed that RBC, PLT and FBG were independent influencing factors for risk stratification of acute PE. RBC was positively correlated with risk stratification, while PLT and FBG were negatively correlated. The area under the ROC curve (AUC) of RBC, PLT and FBG were 0.552 (95% CI: 0.514-0.589), 0.591 (95% CI: 0.554-0.628), and 0.565 (95% CI: 0.527-0.602), with the cut-off value of 4.57 ×10 12/L,182 ×10 9/L and 322.8 mg/dL, respectively. Conclusions:RBC, FBG combined with PLT have clinical predictive value for risk stratification of acute PE.
