A retrospective study of risk factors of patients with acute gastrointestinal injury after polytrauma
10.3760/cma.j.issn.1671-0282.2020.05.010
- VernacularTitle:多发伤后急性胃肠功能损伤的影响因素研究
- Author:
Cong ZHANG
1
;
Hai DENG
;
Zhenwen LI
;
Deng CHEN
;
Liangsheng TANG
;
Han WU
;
Teding CHANG
;
Jingzhi YANG
;
Tinxuan TANG
;
Yao YAO
;
Liming DONG
;
Chunqiu PAN
;
Zhaohui TANG
Author Information
1. 华中科技大学同济医学院附属同济医院创伤外科，武汉 430030
- From:
Chinese Journal of Emergency Medicine
2020;29(5):661-664
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To retrospectively assess the occurrence and risk factors in patients with acute gastrointestinal injury (AGI) after polytrauma.Methods:Totally 430 patients with polytrauma admitted to Tongji Hospital from April 2018 to October 2019 were enrolled as the observation group. According to the diagnostic criteria of AGI, all patients were divided into the AGI group (with AGI) or N-AGI group (without AGI). The patients with abdominal injury or previously suffered from gastrointestinal disease were excluded. The patient's clinical characteristics lab tests results, and the first ISS, APACHEⅡ, SOFA and GCS scores were collected. The differences between different groups were statistically analyzed. The independent risk factors of AGI were analyzed by Logistic regression.Results:65.3% of patients with polytrauma were accompanied by AGI (281/430 cases).There were significant differences between the AGI group and N-AGI group in ISS, GCS, APACHE Ⅱ and SOFA score, PCT or IL-6 level, shock index and length of stay in ICU ( P<0.05). Logistic regression analysis showed that shock, ISS≥16, APACHE Ⅱ≥16, SOFA≥5, GCS≤8 and IL-6>50 pg/mL were the early independent risk factors in patients with ACI after polytrauma. Conclusion:The incidence of AGI in patients after polytrauma is higher, which is related to ischemia, hypoxia, abnormal blood coagulation and stress in the early stage after trauma.
