The predictive value of LCR and BIS monitoring for delayed encephalopathy in acute severe carbon monoxide poisoning
10.3760/cma.j.issn.1671-0282.2020022.010-1
- VernacularTitle:乳酸清除率联合脑电双频指数对一氧化碳中毒迟发性脑病的价值
- Author:
Huan LIU
1
;
Yongjian LIU
;
Qingmian XIAO
;
Yan WANG
;
Wei LI
;
Shuangbao WANG
;
Pu WANG
;
Weizhan WANG
Author Information
1. 河北医科大学附属哈励逊国际和平医院急诊科，衡水 053000
- From:
Chinese Journal of Emergency Medicine
2020;29(4):556-558
- CountryChina
- Language:Chinese
-
Abstract:
Objective:The predictive value of LCR and BIS monitoring for delayed encephalopathy in acute severe carbon monoxide poisoning.Methods:Ninety-four patients with acute severe carbon monoxide poisoning treated in the Harrison International Peace Hospital Affiliated to Hebei Medical University between January 2017 and March 2019 were selected. According to whether DEACMP occurred within 60 days after discharge, the patients were divided into the DEACMP group ( n=33) and good prognosis group ( n=61). LCR and BIS of the two groups at different time points were compared, and the correlation between LCR and BIS was analyzed. The predictive value of LCR, BIS and the combination of the two for DEACMP was analyzed by receiver operating characteristic (ROC) curve. Results:The LCR and BIS of the DEACMP group at day 1t, 3 and 5 were significantly lower than those of the good prognosis group ( P<0.05). Pearson correlation analysis showed that there was a positive correlation between BIS and LCR in the DEACMP group at day 1, 3 and 5 ( r=0.371, P<0.05). There was also a positive correlation between LCR and BIS in the good prognosis group at day 1, 3 and 5 ( r=0.373, P<0.05). ROC curve analysis showed that the areas under the curves of LCR, BIS and the combination of the two for predicting the occurrence of DEACMP in patients with ASCOP were 0.803 (95% CI: 0.707~0.897), 0.941 (95% CI: 0.886~0.997), and 0.949 (95% CI: 0.879~1.000), respectively. Conclusions:LCR combined with BIS is of high predictive value for the occurrence of DEACMP in patients with ASCOP.
