Effect of troponin T decrease rate within 24 h on the prognosis of patients with acute fulminant myocarditis treated with extracorporeal membrane oxygenation
10.3760/cma.j.issn.1671-0282.2020.02.0018
- VernacularTitle:24 h肌钙蛋白T下降率对ECMO治疗的急性暴发性心肌炎患者预后的影响
- Author:
Gang ZHANG
1
;
Xufeng CHEN
;
Jinsong ZHANG
;
Yong MEI
;
Jinru LV
;
Deliang HU
;
Wei LI
;
Huazhong ZHANG
;
Feng SUN
;
Yao REN
;
Wei WANG
;
Xihua HUANG
;
Hui ZHANG
;
Weiwei WANG
Author Information
1. 南京医科大学第一附属医院急诊医学中心，南京 210029
- From:
Chinese Journal of Emergency Medicine
2020;29(2):217-221
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the effect of troponin T decrease rate on the prognosis of patients with acute fulminant myocarditis (AFM) following extracorporeal membrane oxygenation (ECMO).Methods:AFM patients treated with ECMO from April 2015 to December 2018 in our hospital were enrolled in this study. According to the hospital survival, patients were divided into the survival group and non-survival group. The decrease rate of troponin T within 24, 48 and 72 h were compared in the two groups.Results:A total of 18 patients with a mean age of 31 years were enrolled. Fifteen patients survived and 3 patients died with an in-hospital survival rate of 83.3%. The decrease rate of troponin T within 24 h was higher in the survival group than that in the non-survival group (49.36% vs.-59.57%, P<0.05), while there were no statistical differences in 48 h and 72 h between the two groups (57.17% vs.-35.67%, 65.53% vs. 58.96%; all P>0.05). Conclusions:ECMO is an effective treatment for cardiogenic shock or cardiac arrest caused by AFM. The decrease rate of troponin T within 24 h supported by ECMO is higher in the survival group.
