Clinical study of extracorporeal membrane oxygenation and left ventricular function in patients with acute fulminant myocarditis
10.3760/cma.j.issn.1671-0282.2020.02.0017
- VernacularTitle:急性暴发性心肌炎患者体外膜肺氧合治疗后左心收缩功能观察研究
- Author:
Zhongman ZHANG
1
;
Xufeng CHEN
;
Jinsong ZHANG
;
Yong MEI
;
Jinru LV
;
Deliang HU
;
Gang ZHANG
;
Wei LI
;
Huazhong ZHANG
;
Feng SUN
;
Juan WU
;
Yongxia GAO
;
Xihua HUANG
;
Hui ZHANG
Author Information
1. 南京医科大学第一附属医院急诊医学中心，南京 210029
- From:
Chinese Journal of Emergency Medicine
2020;29(2):213-216
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate left ventricular systolic function (LVEF) after extracorporeal membrane oxygenation (ECMO) in patients with acute fulminant myocarditis (AFM).Methods:Seven patients were admitted in the First Affiliated Hospital of Nanjing Medical University from August 2018 to November 2018. All the patients accepted veno-arterial extracorporeal membrane oxygenation (V-AECMO). Complications associated with ECMO and clinical outcome were documented. Transthoracic echocardiography (TTE), single photo emission computed tomography (SPECT), and cardiac magnetic resonance (CMR)were performed to evaluate LVEF.Results:Seven patients were successfully weaned from V-AECMO, 2 of whom had oxygenator leakage, 4 had femoral artery bleeding after decannulation, and 2 had femoral artery pesudoaneurysm. There was no statistical difference in LVEF evaluation between TTE and CMR [(62.4±6.8)% vs (58.9±8.2)%, P >0.05]. CMR and SPECT further revealed myocardial pathological change and coronary arterial blood perfusion. Conclusions:ECMO is recommended in patients with AFM. TTE is simple and easy to perform and is not inferior to CMR in LVEF evaluation. CMR can reflect pathological changes of cardiomyocytes at the cellular level, and SPECT can reflect coronary perfusion.
