Study on the molecular biological effect mechanism of acupuncture at Zusanli Point
10.3760/cma.j.cn115398-20190423-00155
- VernacularTitle:针灸足三里的分子生物学效应机制研究
- Author:
Lizhu LIANG
1
;
Liangjun YANG
;
Xiangzhen FAN
Author Information
1. 四川省德阳市人民医院中医科 618000
- From:
International Journal of Traditional Chinese Medicine
2020;42(11):1125-1129
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the molecular biological effects of Zu-san-li in the treatment of diseases. Methods:Literatures in CNKI, Wan-fang and VIP databases on acupuncture and moxibustion treatment of diseases from January 1, 1999 to April 30, 2019 were retrieved, and the target of Zu-san-li for treating diseases were obtained. The disease enrichment, GO bioprocess enrichment and KEGG pathway enrichment were performed on these targets. Results:A total of 297 articles were included, involving 196 targets. Six diseases, mainly including tumors, nervous system, cardiovascular system, digestive system and other diseases, 18 GO bioprocess related items and 10 signaling pathways, involving signaling pathways such as immunity, cytokines, and gastrin secretion, what those were enriched.Conclusions:Acupuncture at Zu-san-li can treat diseases of multiple systems, which is related to its multi-target and multi-path mechanism. The study can provide a basis for further elucidating the mechanism of action of acupuncture treatment.
