Determination of Zinc gluconate and citric acid in Shanpu-Jianpi granule
10.3760/cma.j.cn115398-20190717-00118
- VernacularTitle:山葡健脾颗粒中葡萄糖酸锌及枸橼酸含量测定研究
- Author:
Weiwei REN
1
;
Jianhong CAI
;
Yuechan ZHANG
;
Xiaofei CHEN
Author Information
1. 江苏省张家港市中医医院药学部，南京中医药大学附属张家港医院药学部 215600
- From:
International Journal of Traditional Chinese Medicine
2020;42(8):783-786
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To develop a method for the determination of Zinc gluconate and citric acid in Shanpu-Jianpi granule. Methods:The air-acetylene was selected as flame type, the detection wavelength was 213.9 nm, the gas flow rate was 0.9 L/min, the burner height was 7.2 mm, and deuterium lamp was used as background correction. The width of passband was 1.0 nm. Titration, sodium hydroxide was used to determine the citric acid with phenolphthalein as an indicator.Results:The content of Zinc Meletin, exhibited good linearity ( r=0.999 8) among the ranges of 0.1-2.0 μg/ml and the average recovery was 94.06% ( RSD=1.67%). The average recovery of citric acid was 94.65% ( RSD=0.91%). Conclusions:The method is simple, accurate and high sensitivity which can be used for determination of Zinc gluconate and citric acid in Shanpu-Jianpi granule.
