Data mining of Yuan-Shaoying's experience on chronic prostatitis based on UPOINT phenotype system
10.3760/cma.j.cn115398-20190323-00194
- VernacularTitle:基于UPOINT系统的袁少英辨治慢性前列腺炎用药规律挖掘研究
- Author:
Xujun YOU
1
;
Wei FU
;
Qing ZHANG
;
Shaoying YUAN
Author Information
1. 广东省深圳市宝安区中医院男科 518101
- From:
International Journal of Traditional Chinese Medicine
2020;42(8):787-792
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To discusses the medication rules of Professor Yuan-Shaoying in the treatment of chronic prostatitis (CP), and to explore the relationship between TCM Syndrome Types and UPOINT system classification. Methods:The TCM syndrome type frequency, UPOINT system classification frequency, drug frequency, four Qi and five flavor meridian tropism frequency were counted by using TCM inheritance auxiliary platform (v2.5). The TCM Syndrome Types and TCM of each type in UPOINT system were obtained according to complex system entropy clustering.Results:A total of 123 prescriptions were included, involving 9 TCM syndrome types, of which the top five were dampness heat stasis syndrome, qi stagnation and blood stasis syndrome, kidney deficiency and blood stasis syndrome, dampness heat downpour syndrome, liver depression and kidney deficiency syndrome. The majority of patients with damp heat stasis syndrome were U-type (urination symptoms) and I-type (infection symptoms), liver depression and kidney deficiency syndrome were mainly p-type (psychological symptoms) and N-type (neural symptoms), most of qi stagnation and blood stasis syndrome were O-type (organ-specific symptoms) and T-type (pelvic floor muscle pain). There were 123 kinds of herbs, and the top five are Shixiaosan ( Wulingzhi + Puhuang), Yanhusuo, licorice, wild grape root and Salvia miltiorrhiza. The drugs mainly include promoting blood circulation and removing blood stasis, clearing heat and tonifying deficiency. The channels of meridian are mainly liver, spleen and kidney. Cold and flat properties are common, while bitter, sweet and pungent are common. According to the U-type classification, the Chinese medicines for clearing heat and detoxification, promoting blood circulation and removing blood stasis were the main drugs, and the top three Chinese medicines were wild grape root, snake berry and licorice root; the P-type was mainly composed of soothing the liver and relieving depression, promoting blood circulation and tonifying the kidney; the top three used frequency were bupleurum, licorice and Paeonia Alba; the O-type was mainly used for promoting Qi, promoting blood circulation, dredging collaterals and relieving pain, and the top three were used frequently. According to the I-type, the main TCMs were clearing heat and activating blood circulation, removing dampness and removing dampness. The top three kinds of TCM were wild grape root, Shixiaosan and liquorice. The N-type was mainly composed of soothing the liver and dredging collaterals, promoting blood circulation and tonifying the kidney, and the top three were bupleurum, Sparganium and Salvia miltiorrhiza; the T-type was mainly the TCM of promoting blood circulation and relieving pain, tonifying liver and kidney; and Yanhusuo, Shixiaosan and Salvia miltiorrhiza were the top three Chinese medicines used frequently. Conclusions:Professor Yuan-Shaoying often takes "promoting Qi, activating blood circulation and removing blood stasis "as the main treatment principle of CP, focusing on regulating the three meridians of liver,spleen and kidney. The relationship between UPOINT system and TCM syndrome types were warranted in further.
