Research progress in treating cardiovascular diseases with the principle of treating phlegm and stasis together
10.3760/cma.j.cn115398-20181126-00235
- VernacularTitle:痰瘀同治法治疗心血管疾病的研究进展
- Author:
Xiang LI
1
;
Huamin ZHANG
;
Lin TONG
;
Lei ZHANG
;
Danli TANG
Author Information
1. 云南中医药大学中药学院2017级硕士研究生,昆明 650500
- From:
International Journal of Traditional Chinese Medicine
2020;42(7):708-711
- CountryChina
- Language:Chinese
-
Abstract:
This paper reviews the recent literatures about the clinical and mechanism researches on the treatment of cardiovascular diseases with the principles of treating phlegm and blood stasis together, which showed that phlegm and blood stasis are the key factors for the occurrence and exacerbation of cardiovascular diseases. This method is often used to treat angina pectoris, acute coronary syndrome, hypertension and hyperlipidemia, which could improve the condition of myocardial ischemia, resist myocardial cell apoptosis, improve vascular endothelial function, regulate the level of inflammatory cytokines, improve myocardial energy metabolism and reduce the level of myocardial injury markers. However, there still lacks of large-scale RCT, the effective components and mechanism of effective compound are not clear and the mechanism research lacks TCM characteristics.