Research progress of anti-tumor mechanism and clinical application of Dahuang-Zhechong Pill
10.3760/cma.j.cn115398-20181226-00190
- VernacularTitle:大黄?虫丸抗肿瘤作用机制及临床应用研究进展
- Author:
Wenli ZHENG
1
;
Yi ZHENG
;
Huijie LI
;
Yuanfu QI
Author Information
1. 山东中医药大学2012级硕士研究生,济南 250014
- From:
International Journal of Traditional Chinese Medicine
2020;42(6):609-611
- CountryChina
- Language:Chinese
-
Abstract:
This paper reviewed the mechanism and clinical application of Dahuang-Zhezhong Pill in Jin Gui Yao Lue. It was found that the anti-tumor effect of Dahuang-Zhezhong Pill was mainly achieved by inhibiting cell proliferation, inducing cell apoptosis, regulating immune function, inhibiting tumor angiogenesis, affecting tumor cell metastasis, and reversing cell resistance. It was used in the treatment of liver cancer, gastric cancer, esophageal cancer, lung cancer and other malignant tumors. Therefore, we should clarify the anti-tumor mechanism, the dominant dosage, the dominant tumor species of Dahuang-Zhezhong Pill, and standardize the dosage of treatment and adverse reactions.