Study on applicability of microbial limit test methods for three kinds of hospital preparations
10.3760/cma.j.cn115398-20190704-00023
- VernacularTitle:三种医院制剂微生物限度检查方法适用性研究
- Author:
Hailing MA
1
;
Yangyang TAO
;
Chunfei XU
;
Yongmei ZHANG
Author Information
1. 南京中医药大学张家港附属医院药剂科 215600
- From:
International Journal of Traditional Chinese Medicine
2020;42(5):469-474
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish microbial limit test methods for three Hospital Preparations: the Jianer Granule, Anti-inflammatory and anti-itching Liquor and Baicao Lotion. Methods:According to the four general principles of the Chinese Pharmacopoeia (edition 2015), to test the applicability for three kinds of hospital preparations with microbial count method using outine method, medium dilution method, membrane filtration method and neutralizer combined membrane filtration method. The applicability test of control bacteria test for three kinds hospital preparations was carried out by routine method, membrane filtration method and neutralizer combined with membrane filtration method. Results:The microbial limit test of Jianer Granule was tested by routine method. The microbial limit test of Anti-inflammatory and anti-itching Liquor was tested by membrane filtration method. The microbial limit test of Baicao Lotion was tested by neutralizer combined with membrane filtration method. Conclusions:Established the methods of microbial limit test for three kinds hospital preparations which are accurate and reliable.
