New progress in antitumor research of non-psychoactive cannabidiol
10.3760/cma.j.cn371439-20200615-00089
- VernacularTitle:非精神活性大麻二酚抗肿瘤研究新进展
- Author:
Shuang WANG
1
;
Yunyun TANG
;
Qi YUE
Author Information
1. 哈尔滨医科大学附属第四医院妇产科 150001
- From:
Journal of International Oncology
2020;47(10):619-623
- CountryChina
- Language:Chinese
-
Abstract:
Cannabidiol is one of the most abundant phytocannabinoids in hemp, which has no psychoactive properties and a variety of pharmacological actions in vivo. Several recent studies indicate that cannabidiol possesses antitumor activity, the diversity of its acting receptor distribution and activation mechanism makes it possible to inhibit tumorigenesis in multiple ways via affecting tumor cell proliferation, inducing apoptosis, inhibiting cell invasion and metastasis, anti-angiogenesis and regulating immune response. Further understanding of the mechanism of cannabidiol in tumors may provide new ideas for the development of new antitumor agents.
