A Case of Gliosarcoma Associated with Neurofibromatosis Type 1.
- Author:
Dae Won KIM
1
;
Jong Tae PARK
;
Jong Moon KIM
;
Tae Young KIM
Author Information
1. Department of Neurosurgery, School of Medicine, Wonkwang University, Iksan, Korea.
- Publication Type:Case Report
- Keywords:
Gliosarcoma;
Neurofibromatosis type I
- MeSH:
Adult;
Brain;
Cafe-au-Lait Spots;
Edema;
Female;
Gliosarcoma*;
Headache;
Humans;
Magnetic Resonance Imaging;
Neurofibromatoses*;
Neurofibromatosis 1*;
Radiotherapy;
Vomiting
- From:Journal of Korean Neurosurgical Society
2001;30(2):221-226
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A rare case of gliosarcoma with neurofibromatosis typeI is presented. The patient was a 33-year-old woman who had headache and vomiting for one week. Multiple neurofibromas over her whole body with many cafe-au-lait spots were present since childhood. At admission, she had no focal neurological deficit and ophthalmologic examination revealed bilateral Lisch nodules. Brain CT and MRI revealed a heterogeneously enhancing mass in the left fronto-parietal region with marked peritumoral edema and mass effect. The tumor was removed gross totally and a gliosarcoma was diagnosed histopathologically. Post operative course was uneventful with resolution of symptom, followed by radiotherapy with 60 Gy. A brief overview is given of this rare case together with the pertinent literature.
