Mechanism of long non-coding RNA GHET1 in tumors of the digestive system
10.3760/cma.j.cn371439-20200209-00024
- VernacularTitle:长非编码RNA GHET1在消化系统肿瘤中的作用机制
- Author:
Yingji MA
1
;
Libin SUN
;
Wensheng QIU
Author Information
1. 青岛大学附属医院肿瘤二科 266011
- From:
Journal of International Oncology
2020;47(5):304-307
- CountryChina
- Language:Chinese
-
Abstract:
Gastric cancer highly expressed transcript 1 (GHET1) is first found in gastric cancer and is a long non-coding RNA (lncRNA). GHET1 is located on chromosome 7q36.1, and is highly expressed in many tumors. High expression of GHET1 is closely related to poor prognosis. Studies have found that GHET1 is involved in regulating many physiological and pathological processes of the body through interaction with microRNAs (miRNAs) or proteins, especially in digestive system tumors, and is expected to become a valuable tumor marker and therapeutic target in the future.
