New research advances of long non-coding RNA in glioma
10.3760/cma.j.issn.1673-422X.2020.02.007
- VernacularTitle:长非编码RNA在神经胶质瘤研究中的新进展
- Author:
Yang NAN
1
;
Yue ZHONG
Author Information
1. 天津医科大学总医院神经外科 300052
- From:
Journal of International Oncology
2020;47(2):98-102
- CountryChina
- Language:Chinese
-
Abstract:
Glioma is the most common primary intracranial tumor which is essentially a polygenic abnormal disease. Long non-coding RNA (lncRNA) is a class of noncoding genes with a length of more than 200 nucleotides. LncRNA plays an important role in tumorigenesis and development by regulating the expression of tumor-related genes or related signaling pathways. The abnormally expressions of lncRNA in gliomas contribute to the diversity of glioma phenotypes. In-depth study of the potential role of abnormally expressed lncRNA in the pathogenesis and pathological grading of gliomas will provide new ideas for clinical targeted treatment of gliomas.
