Preventive and therapeutic effects of common plant drugs on colon cancer and its mechanism
10.3760/cma.j.issn.1673-422X.2020.01.010
- VernacularTitle:常见植物药对结肠癌的防治作用及其作用机制
- Author:
Huiping ZHOU
1
;
Yuhua LI
;
Yuhui WANG
;
Yilong SU
;
Yingying YANG
;
Xiaotian XU
;
Xiaoqun DUAN
Author Information
1. 桂林医学院药学院 541004；南部战区海军第一医院药剂科，湛江 524005
- From:
Journal of International Oncology
2020;47(1):51-55
- CountryChina
- Language:Chinese
-
Abstract:
It is shown that phytochemicals have a protective effect on colon cancer. Curcumin, polysaccharides (apple polysaccharides, mushroom glucans), saponins (paridis saponins, ginsenosides), resveratrol, quercetin and other plant drugs can inhibit colon cancer cell proliferation and promote cell apoptosis through different signaling pathways. In addition, it also has anti-inflammatory, antioxidant, anti-angiogenesis, reduce the toxic side effects of chemotherapy drugs, and reverse the drug resistance of tumor cells. Understan-ding the prevention and cure effect of plant medicine on colon cancer and its possible mechanism can provide more theoretical basis and therapeutic ideas for the clinical prevention and cure of colon cancer.
