Research progress in the role of SR-BI protein in cholesterol gallstones
10.3760/cma.j.cn115396-20200428-00120
- VernacularTitle:SR-BI蛋白在胆囊胆固醇结石中的作用研究进展
- Author:
Libo HAN
1
;
Rongquan XUE
;
Yijun XIA
;
Longfu XI
;
Xiaoyue HAN
;
Jidong BAI
;
Pu ZHAO
;
Qiang MA
Author Information
1. 内蒙古医科大学研究生学院，呼和浩特 010059；内蒙古自治区人民医院肝胆胰脾外科，呼和浩特 010017
- From:
International Journal of Surgery
2020;47(10):702-706
- CountryChina
- Language:Chinese
-
Abstract:
Gallstone is one of the most common diseases in hepatobiliary, cholesterol gallstone is the most common type of gallstone. One of the important causes of gallstone formation is the precipitation of cholesterol crystals caused by cholesterin supersaturation. Scavenger receptor type BI (SR-BI) is a kind of multifunctional membrane receptor protein, which can mediate the selective uptake of cholesterol in liver and then affect the content of cholesterol in bile. Its role in the formation of gallstone has been initially revealed. In this paper, the relationship between the occurrence of cholesterol gallstones and scavenger receptor type B type I was summarized in order to provide new ideas for the further study of the pathogenesis of gallstone.
