Application of FOLFIRINOX regimen in conversion therapy of unresectable pancreatic cancer
10.3760/cma.j.cn115396-20190918-00171
- VernacularTitle:FOLFIRINOX方案在不可切除胰腺癌转化治疗中的应用
- Author:
Di CAO
1
;
Shaocheng LYU
;
Qiang HE
Author Information
1. 首都医科大学附属北京朝阳医院肝胆外科 100020
- From:
International Journal of Surgery
2020;47(5):346-350
- CountryChina
- Language:Chinese
-
Abstract:
Pancreatic cancer is a common malignant tumor of the digestive system with high degree of malignancy and difficulty in diagnosis.Patients with unresectable pancreatic cancer can regain the opportunity to receive surgical treatment with a combination of treatments known as conversion therapy. FOLFIRINOX regimen (Oxaliplatin+ Irinotecan+ 5-Fluorouracil+ Calcium folate) is an effective convesion therapy for unresectable pancreatic cancer, increasing surgical resection rate and prolongation of survival.This review aims to review the application of the FOLFIRINOX regimen in conversion therapy of unresectable pancreatic cancer.