Endothelial inflammatory markers and cerebral microbleeds
10.3760/cma.j.issn.1673-4165.2020.09.010
- VernacularTitle:内皮细胞炎症标志物与脑微出血
- Author:
Xuan LIU
1
;
Rong YIN
;
Huiceng LENG
;
Meiling DAN
;
Dandan MA
;
Yingjie ZHANG
Author Information
1. 解放军第九四〇医院神经内科，兰州 730050；宁夏医科大学临床学院研究生院，银川 750004
- From:
International Journal of Cerebrovascular Diseases
2020;28(9):697-700
- CountryChina
- Language:Chinese
-
Abstract:
Cerebral microbleeds (CMBs) is a imaging manifestation of cerebral small vessel disease. At present, more and more opinions believe that vascular endothelial injury plays an important role in the pathogenesis of CMBs. The destruction of the blood-brain barrier and inflammatory response caused by vascular endothelial dysfunction may promote the occurrence and development of CMBs. At the same time, the deposition of hemosiderin around the lesion of CMBs may also trigger an inflammatory response. However, the relevant mechanisms and causality have not yet been fully elucidated. This article reviews the vascular endothelial inflammatory factors related to CMBs and their mechanism in the pathogenesis of CMBs.
