Endothelial dysfunction and cerebral small vascular disease
10.3760/cma.j.issn.1673-4165.2020.09.009
- VernacularTitle:内皮功能障碍与脑小血管病
- Author:
Xiaoxue CHEN
1
;
Haihong NIE
;
Zhongling ZHANG
Author Information
1. 哈尔滨医科大学附属第一医院神经内科 150001
- From:
International Journal of Cerebrovascular Diseases
2020;28(9):693-696
- CountryChina
- Language:Chinese
-
Abstract:
A large number of studies have confirmed that endothelial dysfunction is one of the important pathogenesis of cerebral small vessel disease (CSVD). Endothelial dysfunction interacts with blood-brain barrier dysfunction, chronic cerebral hypoperfusion, oxidative stress, inflammation and other mechanisms to jointly promote the occurrence and development of CSVD. This article reviews the role of endothelial dysfunction in the pathogenesis of CSVD and its intervention strategies.
