Blood-brain barrier and Alzheimer's disease and vascular cognitive impairment
10.3760/cma.j.issn.1673-4165.2020.06.012
- VernacularTitle:血脑屏障与阿尔茨海默病及血管性认知损害
- Author:
Ni WANG
1
;
Lijuan BAI
;
Xin JIANG
;
Xiaohong CHEN
Author Information
1. 大连医科大学 116004
- From:
International Journal of Cerebrovascular Diseases
2020;28(6):468-471
- CountryChina
- Language:Chinese
-
Abstract:
The integrity of the blood-brain barrier (BBB) is important for maintaining the function of the central nervous system. Its leakage can occur prior to structural changes. At present, the role of BBB leakage abnormalities in the occurrence and development of cognitive impairment has attracted attention, and it has been found that Alzheimer's disease and vascular cognitive impairment are related to BBB leakage abnormalities. This article reviews the pathophysiology of BBB leakage in Alzheimer's disease and vascular cognitive impairment.
