Role of mesenchymal stem cell-derived exosomes in the treatment of stroke
10.3760/cma.j.issn.1673-4165.2020.03.011
- VernacularTitle:间充质干细胞源性外泌体在卒中治疗中的作用
- Author:
Zhenjie SUN
1
;
Maodong WU
;
Qinglun SU
;
Haimin DU
;
Guanghui ZHANG
Author Information
1. 南京医科大学附属连云港医院，连云港市第一人民医院神经内科 222000
- From:
International Journal of Cerebrovascular Diseases
2020;28(3):216-221
- CountryChina
- Language:Chinese
-
Abstract:
Mesenchymal stem cells are a kind of pluripotent stem cells that play a role in stroke treatment mainly through paracrine mechanisms. Recent studies have shown that mesenchymal stem cell-derived exosomes play an important role in reducing post-stroke injury, promoting neural repair and angiogenesis. This article describes the research progress of bone marrow mesenchymal stem cell-derived exosomes in the treatment of stroke, and investigates the therapeutic mechanism and application prospects of exosomes bioactive substances represented by microRNAs.
