Homocysteine and cerebral small vessel disease
10.3760/cma.j.issn.1673-4165.2020.02.010
- VernacularTitle:高半胱氨酸与脑小血管病
- Author:
Yifan JI
1
;
Xiangyu LI
;
Xiaosha LI
;
Qiao YANG
;
Yiyao SONG
;
Haoyuan MA
;
Peiyuan LYU
Author Information
1. 河北医科大学研究生学院，石家庄 050017；河北省人民医院神经内科，石家庄 050051
- From:
International Journal of Cerebrovascular Diseases
2020;28(2):134-139
- CountryChina
- Language:Chinese
-
Abstract:
Homocysteine participates in the methionine cycle in the body and is excreted by the kidneys. Its abnormal elevation increases the risk of cerebrovascular disease. Studies in recent years have shown that hyperhomocysteinemia is closely related to cerebral small vessel diseases and is an independent risk factor for ischemic stroke and cognitive impairment. Because hyperhomocysteinemia is largely reversible, the significance of drug intervention in the prevention and treatment of cerebrovascular disease has gradually been confirmed. This article reviews the relationship between homocysteine and cerebral small vessel diseases in order to provide a reference for the prevention of stroke and dementia.
