Diagnosis and treatment of sepsis associated disseminated intravascular coagulation in children
10.3760/cma.j.issn.1673-4408.2020.10.005
- VernacularTitle:儿童脓毒症相关性弥散性血管内凝血诊疗研究进展
- Author:
Han LI
1
;
Hongjun MIAO
Author Information
1. 南京医科大学附属儿童医院急诊/重症医学科 210008
- From:
International Journal of Pediatrics
2020;47(10):693-697
- CountryChina
- Language:Chinese
-
Abstract:
Sepsis associated disseminated intravascular coagulation is a common complication of sepsis and one of the major causes of increased mortality in pediatric intensive care units.When sepsis occurs, the inflammatory factor storm will cause damage to various tissues and organs of the body, and its complication DIC will further aggravate the organ dysfunction.Therefore, the early detection of DIC is crucial in the treatment of sepsis in children.Since the first diagnostic criteria were proposed by the ministry of health and welfare of Japan (JMHW) in 1983, new diagnostic criteria have been proposed in recent years.At the same time, timely diagnosis is helpful for early intervention to improve the prognosis, so a variety of treatment schemes have also emerged.This article reviews the establishing history, advantages and disadvantages of the diagnostic criteria for sepsis associated DIC, as well as the research progress on various anticoagulants and anticoagulant therapies.
