Application of flow cytometry analyzing basophil activation test in allergy disease
10.3760/cma.j.issn.1673-4408.2020.09.003
- VernacularTitle:流式细胞术分析嗜碱性粒细胞活化试验在过敏性疾病中的应用
- Author:
Yifan LI
1
;
Changshan LIU
Author Information
1. 天津医科大学第二医院儿科 300211
- From:
International Journal of Pediatrics
2020;47(9):607-611
- CountryChina
- Language:Chinese
-
Abstract:
Allergic disease is the common disease that affects human health and life quality.With the development of flow cytometry, basophil activation test(BAT), as an ex vivo challenge test, has become a new method in the diagnosis of allergic disease that IgE mediates.An important step is to establish a standardized BAT method in order to make it available in clinical applications and to explore the mechanisms of allergy in laboratory.This review focuses on the main principles, clinical utility in the diagnosis and management of allergic disease.