Epidemiological study of common pathogens in children with respiratory infection in Children Hospital of Hebei Province
10.3760/cma.j.issn.1673-4408.2020.08.015
- VernacularTitle:河北省儿童医院呼吸道感染患儿常见病原体流行病学研究
- Author:
Liang ZHOU
1
;
Shengwang GE
Author Information
1. 河北医科大学附属河北省儿童医院呼吸科，石家庄 050000
- From:
International Journal of Pediatrics
2020;47(8):578-583
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyse the epidemiological features of 7 common pathogens of children with respiratory tract infections in our hospital in 2019, to provide theoretical support for the prevention and treatment of respiratory tract infection children in Hebei province.Methods:From January 1, 2019 to December 30, 2019, nasopharyngeal aspiration(NPA)or bronchoalveolar lavage fluid(BALF)were collected from 10 186 outpatient and inpatient children with respiratory tract infection in Children Hospital of Hebei Province.Qualitative detection of RSV, ADV, FIu A, Flu B, and PIV Ⅰ, PIV Ⅱ, PIV Ⅲ was performed by immunofluorescence assay based on fluorescent immunomarker monoclonal antibody.The correlation of detection rate with sex, age and season was analyzed statistically.Results:The total detection rate of common respiratory viruses was 24.66% in 2019.The RSV detection rate was the highest(7.60%)than others, followed by Flu A(7.10%), PIV Ⅲ(6.54%), Flu B(2.01%), ADV(0.75%), PIV Ⅰ(0.38%), PIV Ⅱ(0.23%). Flu A and Flu B detections were highest in the first quarter among 1~3 years olds; ADV detection rate was the highest in the fourth quarter; The detection rate of RSV was highest in the fourth quarter among less than 1 years old; PIV I was the most frequently detected in the fourth quarter.PIV Ⅲ had the highest detection rate in the second quarter.RSV infection was positively correlated with age( r=0.200). Detection of Flu A and Flu B was correlated with seasons( r=0.296, r=0.170). Conclusion:The detection rate of respiratory virus has a certain correlation with age and season.
