Progress on the effect and mechanism of formaldehyde on asthma in children
10.3760/cma.j.issn.1673-4408.2020.06.002
- VernacularTitle:甲醛对儿童哮喘的影响及作用机制
- Author:
Jie REN
1
;
Luanluan LI
;
Yixiao BAO
Author Information
1. 上海交通大学医学院附属上海儿童医学中心儿科 200127
- From:
International Journal of Pediatrics
2020;47(6):380-383
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, the prevalence of childhood asthma has been increasing globally.As a common indoor pollutant, formaldehyde is involved in the pathogenesis of asthma, which has drawn increasing attention.However, the results of the current research have not been unified.Some studies have shown that asthma children live in indoor environments where the concentration of formaldehyde is significantly higher than that of healthy children.There are also reports showing that formaldehyde is not an independent risk factor for asthma.The exact results need to be further studied with a larger sample size.In addition, the article concludes the possible mechanism of formaldehyde on asthma from the perspectives of airway inflammation, acquired allergies, and enzymology, providing new ideas for the prevention and treatment of asthma.
