Progress of pertussis toxin
10.3760/cma.j.issn.1673-4408.2020.05.004
- VernacularTitle:百日咳毒素的研究进展
- Author:
Wenjing GUO
1
;
Yingxue ZOU
Author Information
1. 天津医科大学研究生院 300070
- From:
International Journal of Pediatrics
2020;47(5):312-316
- CountryChina
- Language:Chinese
-
Abstract:
Pertussis is an acute respiratory infectious disease caused by Bordetella pertussis.In recent years, pertussis reappearance makes it become one of the important diseases affecting human health.Pertussis toxin is an important virulence factor produced by Bordetella pertussis.It is an important component of acellular pertussis vaccine, and is related to most clinical symptoms and fatal pertussis.This paper reviews the molecular structure and pathogenesis of pertussis toxin.