Application of plasma exchange in severe Henoch-Schonlein purpura
10.3760/cma.j.issn.1673-4408.2020.04.010
- VernacularTitle:血浆置换在重型过敏性紫癜中的应用
- Author:
Huijuan MA
1
;
Xinhui YUAN
;
Yuning LI
Author Information
1. 兰州大学第一临床医学院 730000
- From:
International Journal of Pediatrics
2020;47(4):259-262
- CountryChina
- Language:Chinese
-
Abstract:
Henoch-Schonlein purpura (HSP) is a type of systemic leucocytoclastic vasculitis mediated by IgA immune complex deposition, which mainly affects the skin, joints, gastrointestinal tract and small blood vessels in the glomeruli.It is a common systemic vasculitis in children.Due to severe complications of HSP, conventional clinical medicine has limited efficacy in some serious, even life-threatening or organ dysfunction cases, such as advanced renal insufficiency, fatal gastrointestinal bleeding, nervous vasculitis, pulmonal bleeding, etc.As an adjunctive therapy, plasma exchange has led to significant results for this type of HSP.In this paper, the status of plasma exchange in HSP treatment was reviewed.