Neurological disease and microbiota-gut-brain axis
10.3760/cma.j.issn.1673-4408.2020.04.008
- VernacularTitle:微生物-肠-脑轴与神经系统疾病
- Author:
Huating ZHANG
1
;
Yong HU
Author Information
1. 上海市儿童医院，上海交通大学附属儿童医院新生儿科 200062
- From:
International Journal of Pediatrics
2020;47(4):252-254
- CountryChina
- Language:Chinese
-
Abstract:
The gut microbiota play an important role in the bidirectional interactions between the gut and the nervous system, which is called the microbiota-gut-brain axis.The short-chain fatty acids, neurotransmitters, Vagal nerve and the hypothalamus-pituitary-adrenal axis are different ways of affecting neurological diseases, including Alzheimer′s disease, Parkinson′s disease, depression disease; childhood autism and neonatal encephalopathy.Based on the studies of neurological diseases, this paper analyzes the role of gut microbiota in diseases, and provides a modern consideration for the further research and clinical application of microbiota-gut-brain axis.
