Periodic fever, aphthous stomatitis, pharyngitis and adenitis syndrome
10.3760/cma.j.issn.1673-4408.2020.04.012
- VernacularTitle:周期性发热-阿弗他口炎-咽炎-淋巴结炎综合征研究进展
- Author:
Yuanyuan LI
1
;
Biquan CHEN
Author Information
1. 安徽省儿童医院感染科，合肥 230051
- From:
International Journal of Pediatrics
2020;47(4):267-270
- CountryChina
- Language:Chinese
-
Abstract:
Periodic fever, aphthous stomatitis, pharyngitis and adenitis(PFAPA)syndrome which is generally considered to be an autoinflammatory disease with multiple etiologies and heterogeneous inheritance, is the most common cause of periodic fever in childhood.So far, many possible causative factors have been explored, including infectious agents, immunologic mechanisms and genetic predisposition, but the exact etiology remains unclear.At the same time, due to the lack of standardized diagnosis and treatment standards, many children received unnecessary examinations and unreasonable treatment.This review aims to analyze PFAPA syndrome in detail in terms of clinical characteristics, pathogenesis, diagnosis, differential diagnosis and treatment in order to establish the more specific diagnostic criteria and the more standardized treatment to enable children with PFAPA to receive timely diagnosis and appropriate treatment.
