Progress in detection of serum antibodies related to myasthenia gravis in children
10.3760/cma.j.issn.1673-4408.2020.04.011
- VernacularTitle:儿童重症肌无力相关血清抗体检测的研究进展
- Author:
Qian YANG
1
;
Rongjun LIN
Author Information
1. 青岛市妇女儿童医院 266000
- From:
International Journal of Pediatrics
2020;47(4):263-266
- CountryChina
- Language:Chinese
-
Abstract:
Myasthenia gravis(MG)is an autoimmune disease, and local or systemic muscle weakness is the main symptom.The main auxiliary tests are serological, pharmacological and electrophysiological tests.Autoantibodies are the most important biomarkers to guide the diagnosis of myasthenia gravis.The clinical features and autoantibodies of myasthenia gravis in children were different from those in adults.Therefore, this paper summarizes the clinical significance of the main autoantibodies acetylcholine receptor(AChR)antibody, muscle specific kinase(MuSK)antibody, low density lipoprotein receptor associated protein 4(LRP-4)antibody and other related antibodies in children with myasthenia gravis, which has certain guiding significance for the diagnosis and individualized treatment of myasthenia gravis.
