Progress of extracellular vesicles in the pulmonary inflammatory diseases
10.3760/cma.j.issn.1673-4408.2020.03.002
- VernacularTitle:细胞外囊泡在肺部炎症性疾病中的研究进展
- Author:
Junyan JI
1
;
Yuqing CAI
;
Lanfang TANG
Author Information
1. 浙江大学医学院附属儿童医院呼吸科,杭州 310051
- From:
International Journal of Pediatrics
2020;47(3):155-159
- CountryChina
- Language:Chinese
-
Abstract:
Extracellular vesicles are a kind of membrane structures deriving from cells, which exist widely in urine, blood, saliva, milk, cerebrospinal fluid, amniotic fluid and other body fluid.Extracellular vesicles contain nucleic acid, enzymes, proteins and other bioactive molecules, which can convey the biological information to target cells through a variety of modes and participate in the pathophysiological processes of target cells.In recent years, it is considered that extracellular vesicles are associated with the pathogenesis of inflammatory disease of pulmonary such as asthma, chronic obstructive pulmonary disease and acute lung injury/acute respiratory distress syndrome, and have potential therapeutic value through a large body of research.