Progress on asparaginase-associated pancreatitis
10.3760/cma.j.issn.1673-4408.2020.03.008
- VernacularTitle:门冬酰胺酶相关性胰腺炎的研究进展
- Author:
Chenxi LIU
1
;
Shuhong SHEN
Author Information
1. 上海交通大学医学院附属上海儿童医学中心血液肿瘤科 200127
- From:
International Journal of Pediatrics
2020;47(3):180-183
- CountryChina
- Language:Chinese
-
Abstract:
Acute lymphoblastic leukemia(ALL)is the most common childhood malignancy.As an essential component of multiagent chemotherapy, asparaginase(ASP)has significantly improved the remission rate and event-free survival rate of children with ALL since its application in clinical practice.However, there are many adverse events due to ASP, including asparaginase-associated pancreatitis(AAP). The mechanisms behind and the risk factors predisposing AAP are unknown.This review summarizes the latest research progresses on AAP.
