Research advances in animal models of cow's milk protein allergy
10.3760/cma.j.issn.1673-4408.2020.02.002
- VernacularTitle:牛奶蛋白过敏动物模型的研究进展
- Author:
Fangfei XIAO
1
;
Yizhong WANG
Author Information
1. 上海交通大学附属儿童医院上海市儿童医院消化感染科 200062
- Keywords:
Cow's milk protein allergy;
Animal models
- From:
International Journal of Pediatrics
2020;47(2):77-81
- CountryChina
- Language:Chinese
-
Abstract:
Cow's milk protein allergy (CMPA) is the most common food allergy among infants and young children,which has an increasing incidence in recent years.Performing suitable animal experiments is a key to study CMPA,but currently there aren't proper models consistent with human physiological sensitization process.Ideal animal models can serve as critical tools to reveal the mechanisms of CMPA and develop preventive and therapeutic approaches.Animal species and strains,different types of the models,biological detection methods and evaluation are reviewed in this paper.It also summarizes characteristics of animal models,which will provide a reference for basic and applied researches of CMPA.
