Clinicopathological characteristics of non-Hodgkin lymphoma in Shandong province: analysis of 2 886 cases
10.3760/cma.j.issn.1009-9921.2020.02.011
- VernacularTitle:山东省非霍奇金淋巴瘤2 886例临床病理特征分析
- Author:
Ti WANG
1
;
Qiujing ZHANG
;
Yuhong LIU
;
Qingqing ZHU
;
Jujie SUN
;
Jianbo ZHANG
;
Jie LIU
;
Bao SONG
Author Information
1. 山东第一医科大学（山东省医学科学院） 山东省肿瘤医院内三科，济南 250117（工作单位为山东省泗水县人民医院肿瘤科，273200）
- From:
Journal of Leukemia & Lymphoma
2020;29(2):117-120
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinicopathological characteristics of non-Hodgkin lymphoma (NHL) in Shandong province.Methods:The clinicopathological data of 2 886 NHL cases in Shandong Cancer Hospital from January 2002 to December 2017 were retrospectively analyzed, the clinicopathological characteristics of patients were summarized and compared with other regions in China and abroad.Results:The median age of all NHL cases was 52 years old (4-90 years old), and the ratio of male to female was 1.57∶1. The subtypes distribution analysis revealed that B-cell NHL (B-NHL) accounted for 66.7% (1 925 cases) of all cases and T-cell NHL (T-NHL) accounted for 27.3% (788 cases) of all cases. The common subtypes were diffuse large B-cell lymphoma (36.0%, 1 039/2 886), NK/T-cell lymphoma (8.8%, 254/2 886), follicular lymphoma (8.2%, 237/2 886) and peripheral T-cell lymphoma (7.4%, 214/2 886). Of all the cases, the nodal lymphomas accounted for 45.8% (1 322 cases) and the extra nodal lymphomas accounted for 54.2% (1 564 cases); there were 389 patients (13.5%) with stage Ⅰ, 678 patients (23.5%) with stage Ⅱ, 975 patients (33.8%) with stage Ⅲ, and 722 patients (25.0%) with stage Ⅳ. The distribution of NHL subtypes in Shandong province was consistent with the domestic multicenter study. However, T-NHL subtype ratio was significantly higher than the foreign studies.Conclusions:The overall incidence of NHL in Shandong province of China is dominated by middle-aged people, and the proportion of B-NHL is higher than that of T-NHL. The distribution of NHL subtypes in Shandong province of China are different from those in the European and American countries, but are roughly consistent with the domestic multicenter study.
