Research progress on trogocytosis of immune cell in transplantation immunity
10.3969/j.issn.1674-7445.2021.01.017
- VernacularTitle:免疫细胞互噬作用在移植免疫中的研究进展
- Author:
Yang ZHAO
1
;
Lin ZHOU
;
Qiang HE
Author Information
1. Department of Hepatobiliary, Pancreatic and Splenic Surgery, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China
- Publication Type:Research Article
- Keywords:
Trogocytosis;
Immune cell;
Immune regulation;
Phagocytosis;
Antigen presentation;
Transplantation immunity;
Tumor immunity;
Cell killer
- From:
Organ Transplantation
2021;12(1):109-
- CountryChina
- Language:Chinese
-
Abstract:
Trogocytosis is a process of exchanging part of the membrane fragment or cytoplasmic content of cells through direct contact, and it's an interaction mechanism that exists between cells. Immune cell can obtain some characteristics of other cells through trogocytosis, and the new cells generated through trogocytosis may play an important role in the induction of graft immune tolerance. In this article, the origin and development of research on cell trogocytosis, mechanism of cell trogocytosis and biological significance of trogocytosis of immune cell were reviewed.
