Research progress on the relationship between high fluoride exposure and cardiovascular system injury
10.3969/j.issn.1006-2483.2021.01.023
- VernacularTitle:高氟暴露对心血管系统损伤的研究进展
- Author:
Wenfeng LI
1
;
Yang WANG
1
;
Fang LI
1
;
Changchun HOU
1
;
Lichun CAO
2
Author Information
1. Tianjin Center for Diseases Control and Prevention, Tianjin 300011, China
2. Dazhangzhuang Community Healthcare Service Center, Beichen District of Tianjin, Tianjin 300405, China
- Publication Type:Journal Article
- Keywords:
Fluorosis;
Cardiovascular;
Hypertension;
Hyperlipidemia
- From:
Journal of Public Health and Preventive Medicine
2021;32(1):96-99
- CountryChina
- Language:Chinese
-
Abstract:
High fluoride exposure induces not only skeletal damage such as dental fluorosis and skeletal fluorosis, but also injury on the cardiovascular system. In this article, we elaborated on the effects of high fluoride exposure on cardiovascular diseases such as heart injury, vascular sclerosis, hypertension and hyperlipidemia by reviewing domestic and foreign literatures in the last decade. We analyzed the damage effects and mechanisms of high fluoride exposure from the perspectives of population epidemiology, animal experiments and in vitro cell experiments, and proposed that prospective cohort studies on the effects of high fluoride exposure on cardiovascular system damage should be further strengthened. This paper provides a scientific basis and new ideas for the prevention and treatment of endemic fluorosis and cardiovascular diseases.