Analysis of the correlation between smoking, white blood cell counts and serum bilirubin levels in male radiation workers
10.3969/j.issn.1006-2483.2021.01.017
- VernacularTitle:吸烟、白细胞计数与男性放射工作人员血清胆红素水平的关联性
- Author:
Hualin SU
1
;
Tian XU
2
;
Wenjun YIN
2
;
Fang HE
2
;
Bifeng LU
2
;
Ansheng LIU
2
;
Zhiwei PAN
2
Author Information
1. Center for Disease Control and Prevention of Minhang District, Shanghai 201101, China
2. Wuhan Prevention and Treatment Center for Occupational Diseases, Wuhan 430015, China
- Publication Type:Journal Article
- Keywords:
Smoking;
White blood cell counts;
Serum bilirubin;
Radiation workers
- From:
Journal of Public Health and Preventive Medicine
2021;32(1):67-71
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between smoking, white blood cell counts, and serum bilirubin levels in male radiation workers, and to explore the role of systemic inflammatory response in the changes of serum bilirubin level induced by smoking. Methods Occupational health examination data of 1 320 male radiation workers in a medical institution was collected. Linear regression analysis method was used to analyze the correlations between smoking and white blood cell counts, between smoking and serum bilirubin levels, and between white blood cell counts and serum bilirubin levels. Results There was a significant positive correlation between smoking and white blood cell counts (P< 0.05). Both smoking and white blood cell counts were significantly negatively correlated with serum bilirubin levels (P < 0.05). However, after adjusting the white blood cell counts, the correlation between smoking and serum bilirubin levels was not statistically significant (P > 0.05). By dividing white blood cell counts into two groups, an inverse correlation was found between smoking and serum bilirubin levels in the high white blood cell count group (P < 0.05). Conclusion Serum bilirubin may be an effective indicator of early health damage caused by smoking in male radiation workers. Smoking may induce inflammatory reaction, thus deplete serum bilirubin and cause its levels to drop.
