Pharmacological Effect and Substance Basis of Neutral Blood-activating and Stasis-removing Traditional Chinese Medicine
10.13422/j.cnki.syfjx.20192207
- VernacularTitle:平性活血化瘀中药物质基础与药理作用的研究进展
- Author:
Qiong MO
1
;
Er-wei HAO
1
;
Wen-hui QIN
1
;
Xiao-tao HOU
1
;
Jia-gang DENG
1
;
You WU
1
Author Information
1. Guangxi Key Laboratory for Pharmacodynamics Research of Traditional Chinese Medicine, Guangxi University of Chinese Medicine, Nanning 530001, China
- Publication Type:Research Article
- Keywords:
blood-activating and stasis-removing Chinese medicine;
neutral herb;
material basis;
pharmacological effect;
research progress
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2020;26(1):205-216
- CountryChina
- Language:Chinese
-
Abstract:
By reviewing the 2015 edition of Chinese Pharmacopoeia, the author collected 37 neutral blood-activating and stasis-removing traditional Chinese medicines. And by retrieving literatures on relevant material basis and pharmacological effects on CNKI, the author organized and summarized their chemical composition and pharmacological effects. Neutral blood-activating and stasis-removing traditional Chinese medicines are rich in chemical components, such as flavonoids, steroids and sugars. At the same time, it has a variety of pharmacological effects, including anti-platelet aggregation and anti-thrombotic mechanism, anti-atherosclerosis, inhibition of ischemia-perfusion injury, anti-tumor, anti-fibrosis, liver protection, anti-inflammatory analgesia, blood pressure reduction and immune regulation. It is widely used in the treatment of liver fibrosis, cardiovascular disease, liver cancer, uterine cancer, hypertension, hyperlipidemia and other diseases. Nowadays, as people has paid increasing attention to neutral herbs, studies on traditional Chinese medicines for activating blood circulation and removing blood stasis have been further deepened, which provides a better development prospect for neutral blood-activating and stasis-removing traditional Chinese medicines. From the perspective of medicinal properties, the authors systematically collected and summarized the pharmacological effects and material basis of neutral blood-activating and stasis-removing traditional Chinese medicines. This article provides theoretical guidance for the clinical application of neutral blood-activating and stasis-removing traditional Chinese medicines and new medicine research ideas for neutral blood-activating and stasis-removing traditional Chinese medicines.
