Chemical Constituents of Pericarps of Zanthoxylum bungeanum
10.13422/j.cnki.syfjx.20192112
- VernacularTitle:花椒果皮化学成分分离鉴定
- Author:
Shuang LYU
1
;
Jia-huan CHEN
2
;
Tao ZHANG
2
;
Jin-guang SI
2
;
Lu FU
2
;
Hui-ming HUA
1
;
Xiao-qiu LIU
1
;
Zhong-mei ZOU
2
Author Information
1. Shenyang Pharmaceutical University, Shenyang 110016, China
2. Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union College, Beijing 100193, China
- Publication Type:Research Article
- Keywords:
Zanthoxylum bungeanum;
pericarps;
95%ethanol extract;
(1S, 3S)-1-methyl-1, 2, 3, 4-tetrahydro-β-carboline-3-carboxylic acid
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2020;26(1):133-138
- CountryChina
- Language:Chinese
-
Abstract:
Objective::To study the chemical constituents of pericarps of Zanthoxylum bungeanum. Method::The dried pericarps of Z. bungeanum were smashed, and then extracted and concentrated in 95%ethanol to obtain the total extract. The total extract was loaded on a silica gel CC, eluted with different polar solvents in sequence, and then concentrated to obtain corresponding parts. The methylene chloride fraction and the n-butanol fraction were separated and purified by silica gel column chromatography, Sephadex LH-20 gel column chromatography, ODS column chromatography, semi-preparative HPLC, etc. And their structures were identified based on physicochemical properties and various spectroscopic methods. Result::Fourteen compounds were isolated from the dichloromethane fraction and the n-butanol fraction of the Z. bungeanum and identified as(1S, 3S)-1-methyl-1, 2, 3, 4-tetrahydro-β-carboline-3-carboxylic acid(1), (3S)-1, 2, 3, 4-tetrahydro-β-carboline-3-carboxylic acid(2), apigenin-7, 4′-dimethyl ether(3), genkwanin(4), lcariside F2(5), breyniaionoside A(6), 3-methoxyphenethyl alcohol-4-O-β-D-glucopynanoside(7), 1-O-β-D-glucopyranosyloxy-3-methoxy-5-hydroxybenzene(8), orcinol-O-β-D-glucopyranoside(9), syringin(10), 4-[(3S)-3-hydroxybutyl]-2-methoxyphenyl-β-D-glucopyranoside(11), (+ )-lyoniresinol-3a-O-β-D-glucopyranoside(12), 2-methylpropanyl-6-O-β-D-apiofuranosyl-β-D-glucopyranoside(13)and(E)-6-hydroxy-2, 6-dimethylocta-2, 7-dienoic acid(14). Conclusion::All compounds were isolated from Z. bungeanum for the first time, and compounds 1-4, 12 and 14 were isolated from this genus for the first time.
