The role of microRNA in autoimmune liver diseases
DOI:10.3969/j.issn.1001-5256.2021.01.047
- VernacularTitle:microRNA在自身免疫性肝病中的作用
- Author:
Mengqiang CAI
1
;
Sutong LIU
;
Junying LIU
;
Lihui ZHANG
;
Wenxia ZHAO
Author Information
1. The First Clinical Medical College, Henan University of Traditional Chinese Medicine, Zhengzhou 450000, China
- Publication Type:Research Article
- Keywords:
microRNAs;
Hepatitis, Autoimmune;
Liver Cirrhosis, Biliary;
Cholangitis, Sclerosing
- From:
Journal of Clinical Hepatology
2021;37(1):212-215
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNA(miRNA) affect various biological processes such as cell differentiation, proliferation, and apoptosis by inhibiting the translation of target genes after transcription and are widely involved in the regulation of immune and inflammatory responses in organisms. Autoimmune liver diseases are a group of chronic inflammatory diseases of the hepatobiliary system mediated by abnormal immunity, and abnormal immune inflammatory response of liver tissue with the involvement of miRNA is closely associated with the development and progression of autoimmune liver diseases. This article reviews the current research advances in miRNA in autoimmune liver diseases.
