Impact of obstructive sleep apnea on nonalcoholic fatty liver disease
DOI:10.3969/j.issn.1001-5256.2021.01.042
- VernacularTitle:阻塞性睡眠呼吸暂停对非酒精性脂肪性肝病的影响
- Author:
Qingqing XU
1
;
Haiying TANG
;
Jingwei MAO
Author Information
1. Department of Gastroenterology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116011, China
- Publication Type:Research Article
- Keywords:
Sleep Apnea, Obstructive;
Non-alcoholic Fatty Liver Disease;
Hypoxia
- From:
Journal of Clinical Hepatology
2021;37(1):192-195
- CountryChina
- Language:Chinese
-
Abstract:
Obstructive sleep apnea (OSA) may induce chronic intermittent hypoxia, which may lead to the disorders of multiple systems and organs and even sudden cardiac death in severe cases. Besides respiratory, cardiovascular, endocrine, and metabolic diseases, OSA is also closely associated with nonalcoholic fatty liver disease (NAFLD). This article briefly describes the current status of OSA and NAFLD, introduces the impact of OSA on NAFLD, and reviews the mechanisms of OSA in NAFLD. It is pointed out that clarifying the mechanisms of OSA in affecting NAFLD and discovering potential prevention and treatment targets for NAFLD from the aspect of OSA are of great significance in delaying and even blocking the progression of NAFLD.
