Biomarkers for the early diagnosis of hepatocellular carcinoma
DOI:10.3969/j.issn.1001-5256.2021.01.038
- VernacularTitle:肝细胞癌早期诊断中的生物标志物
- Author:
Xichen LIU
1
;
Yiying WANG
;
Manman TONG
;
Junjie QIN
Author Information
1. Department of Hepatology, The First Hospital of Jilin University, Changchun 130021, China
- Publication Type:Research Article
- Keywords:
Carcinoma, Hepatocellular;
Early Diagnosis;
Biomarkers, Tumor
- From:
Journal of Clinical Hepatology
2021;37(1):176-179
- CountryChina
- Language:Chinese
-
Abstract:
Patients with advanced hepatocellular carcinoma (HCC) often have poor prognosis, and early diagnosis and effective treatment measures can significantly improve the survival rate of patients. At present, alpha-fetoprotein (AFP) is the most widely used serum marker for the diagnosis of HCC in the world; however, no increase in AFP was found in some HCC patients. This article analyzes the application potential of AFP, hepatitis B core-related antigen, liquid biopsy technology, microRNA, long non-coding RNA, and exosomes in the early diagnosis of HCC and reviews related research advances, so as to provide a basis for exploring new methods for the early diagnosis of HCC.
