Clinical characteristics of patients with malignant tumors combined with COVID-19
10.3969/j.issn.1006-2483.2020.06.003
- VernacularTitle:恶性肿瘤合并新型冠状病毒患者临床特征分析
- Author:
Mengting GAO
1
;
Lei YUAN
1
;
Haiyan SHAO
2
;
Fengbo XI
2
Author Information
1. Information Center, Renmin Hospital of Wuhan University, Wuhan , Hubei 430060,China
2. Shanghai Municipal Center for Disease Control & Prevention, Shanghai 200336, China
- Publication Type:Journal Article
- Keywords:
COVID-19;
Cancer;
Severe clinical events;
Clinical characteristics
- From:
Journal of Public Health and Preventive Medicine
2020;31(6):10-14
- CountryChina
- Language:Chinese
-
Abstract:
Objective To retrospectively analyze the clinical characteristics of patients with malignant tumors combined with new coronavirus pneumonia (COVID-19), and to provide a scientific basis for clinical treatment. Methods SPSS 20.0 was used for data analysis. The t-test was used for quantitative data, and chi-square test/Fisher-exact test was used for qualitative data. Binary logistic regression was used for multivariate analysis, and the correlation coefficient was used for multicollinearity test before regression analysis. Results A total of 61 COVID-19 infected cancer patients were included in this study. Their average age was 62.2±12.12. The most common admission symptoms were fever (54.1%), fatigue (39.3%), and cough (37.7%). The rate of the patients with severe COVID-19 was 54.1%. Having 3 or more complications (OR: 2.07, 95%CI: 3.14-2698.12), fever (OR: 12.22, 95%CI: 1.20-86.70), low percentage of lymphocytes (OR: 15.56, 95%CI: 1.78-136.24) and low serum albumin level (OR: 254.64, 95%CI: 8.56-7576.41) were risk factors for COVID-19 severity. The fatality rate of the subjects was 8.2%, and the average hospital stay was 26.7±19.69 days. Furthermore, the severity of COVID-19 had a statistically significant impact on the average hospital stay (t=-3.48, P<0.01). Conclusion Patients with malignant tumors combined with COVID-19 have a higher severity rate, fatality rate, and average hospital stay than ordinary COVID-19 patients. Underlying diseases, fever, low lymphocyte percentage, and low serum albumin levels are the factors for the increase of the illness severity in patients with malignant tumors combined with COVID-19.
