New advances in baicalein's antitumor effects and mechanisms
10.12206/j.issn.1006-0111.202004030
- VernacularTitle:黄芩素抗肿瘤作用及其机制研究新进展
- Author:
Jiaxiao DONG
1
;
Yongsheng JIN
2
;
Ying CAO
1
Author Information
1. Department of Pharmacy, Zhangjiagang Hospital Affiliated to Soochow University, Suzhou 215600, China.
2. School of Pharmacy, Naval Medical University, Shanghai 200433, China.
- Keywords:
baicalein;
anti-tumor;
mechanism
- From:
Journal of Pharmaceutical Practice
2021;39(1):9-12
- CountryChina
- Language:Chinese
-
Abstract:
Baicalein (BE) is an active ingredient derived from the root of Scutellaria baicalensis Georgi. It is a polyhydroxyflavonoid in structure and has many biological activities. Among them, the antitumor effects of baicalein have received widespread attention. It exerts anti-tumor effects by inducing tumor cell apoptosis and invasion, inhibiting tumor angiogenesis, and eliminating free radicals. This article reviews the most recent research works of baicalein in its anti-tumor effects and mechanisms. It is aimed to provide a theoretical basis for the search and development of potential new anti-tumor drugs.
