Research progress in new formulations of norcantharidin
10.12206/j.issn.1006-0111.202004038
- VernacularTitle:去甲斑蝥素新型制剂研究进展
- Author:
Sifan HUANG
1
;
Yuansheng ZHANG
2
;
Jianming CHEN
1
;
Xin WU
2
,
3
Author Information
1. School of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.
2. Shanghai Weier Laboratory, Shanghai 201712, China.
3. School of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China
- Keywords:
norcantharidin;
microspheres;
nanoparticles;
liposomes;
microemulsions
- From:
Journal of Pharmaceutical Practice
2021;39(1):1-3
- CountryChina
- Language:Chinese
-
Abstract:
Objective To review the research progress in new formulations of norcantharidin. Methods The foreign and domestic literature search in the new formulations of norcantharidin was conducted. The research and development of norcantharidin formulations were summarized and commented. Results The drug delivery systems, such as microspheres, nanoparticles, liposomes, and microemulsions, have great development potential as the new formulations for norcantharidin. Conclusion Norcantharidin is an excellent anti-tumor drug. The traditional injections and tablets have serious side effects in clinical application. The new formulations reduced the renal and urinary toxicity and side effects. Those formulations provided better therapeutic effects as target medication. Therefore, the new norcantharidin formulations have great development prospects.
