Clinical Significance and Method of Measuring Lung Fluid Viscosity and Surface Tension
10.16156/j.1004-7220.2020.03.17
- VernacularTitle:肺内液黏度和表面张力测量的临床意义与测量方法
- Author:
Yuanyang LIU
1
;
Zhenglong CHEN
2
;
Yuanlin SONG
3
;
Xiangyue HUANG
1
;
Chunyuan ZHANG
1
;
Zhaoyan HU
2
Author Information
1. School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology
2. School of Medical Instrument, Shanghai University of Medicine and Health Sciences
3. Department of Respiration, Zhongshan Hospital Affiliated to Fudan University
- Publication Type:Journal Article
- Keywords:
airway mucus;
viscosity;
surface tension;
rheology;
ventilator-induced lung injury
- From:
Journal of Medical Biomechanics
2020;35(3):E378-E384
- CountryChina
- Language:Chinese
-
Abstract:
Pulmonary fluid refers to a thin and continuous liquid layer mainly consisting of airway mucus and lining liquid on the inner surface of alveoli, which is essential for maintaining a healthy lung. The clinical significance of rheological properties of pulmonary fluid in airway stability, pulmonary barrier and clearance functions, ventilator induced lung injury and surfactant replacement therapy in infant respiratory distress syndrome was introduced in this paper. Furthermore, a variety of classical methods for measuring surface tension and liquid viscosity, such as Langmuir-Wilhelmy balance, captive bubble method, glass capillary viscometer and rotational viscometer, and emerging techniques (e.g. particle tracking microrheometer and axisymmetric drop shape analysis) were reviewed, and their advantages and drawbacks were also compared, in order to provide an important reference for the assisted diagnosis and treatment of lung diseases in clinical practice.
