Sensitivity Analysis of Flow Diverter Treatment of Intracranial Aneurysm Using Porous Media Model
10.16156/j.1004-7220.2020.06.11
- VernacularTitle:基于多孔介质模型的血流导向装置栓塞颅内动脉瘤的敏感性
- Author:
Bin BAI
1
;
Yunzhang CHENG
1
;
Hui GAO
1
;
Nan LÜ
2
;
Linjing PENG
1
Author Information
1. Shanghai Engineering Research Center of Interventional Medical Devices, University of Shanghai for Science and Technology
2. Department of Neurosurgery, First Affiliated Hospital of Naval Military Medical University (Changhai Hospital of Shanghai)
- Publication Type:Journal Article
- Keywords:
flow diverter;
intracranial aneurysm;
porous media model;
hemodynamics;
numerical simulation
- From:
Journal of Medical Biomechanics
2020;35(6):E718-E724
- CountryChina
- Language:Chinese
-
Abstract:
Objective To simulate the hemodynamic effects of different flow diverters (FD) parameters by using computational fluid dynamics (CFD) technology, so as to develop a more reasonable FD embolization strategy before operation. Methods The porous media model was used to simulate the process of FD implantation into aneurysms, and the initial values of its own unique porous media momentum source parameters (permeability and inertial resistance) were calculated for a specific FD (Tubridge).The changes of hemodynamic parameters such as blood flow velocity, wall shear stress (WSS), volume flow and pressure of aneurysm-roof were compared under different situations (initial values of 80%, 90%, 100%, 110% and 120%), and the sensitivity analysis on hemodynamic parameters of patient-specific intracranial aneurysms (IA) for the porous media model was further conducted. Results The sensitivity of IA hemodynamic parameters to the permeability of porous media model was as follows: WSSparent-artery＞WSSaneurysm＞paneurysmal-roof, but the sensitivity to inertia resistance was relatively lower. Conclusions By using the porous media model, different metal coverages (MC) of FD could be simulated by choosing different permeability parameters, so it is necessary to adjust specific permeability settings during modeling of FD with different MC.
